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Value of Magnetic Resonance Imaging-Based Measurements of Hippocampal Formations in Patients with Partial Epilepsy Arch Neurol 51:130-138, Adam,C.,et al, 1994 See this aricle in Pubmed Article Abstract Hippocampal atrophy was present in 70%of patients with cryptogenic temporal lobe epilepsy(TLE)(n=40),44%of patients with symptomatic TLE(n= 9),29%of patients with extratemporal epilepsy(n=14),and 6%of unclassified patients(n=16).In the cryptogenic TLE category,HA was marked and usually concordant(93%)with electroencephalographic lateralization.Hippocampal atrophy was often mild in the extratemporal epilepsy category.With the use of a wider confidence interval(+/-3.1 SD instead of+/-2.2 SD),HA specificity for TLE increased to 93%,HA specificity for lateralizing cryptogenic TLE reached 96%,and HA sensitivity for cryptogenic TLE stood almost unchanged(68%).We found a link between early convulsions and HA occurrence.Hippocampal atrophy is a marker for TLE.Dual pathologic findings are detected in 44%of symptomatic TLE cases.Mild HA is rarely associated with extratemporal epilepsy.Magnetic resonance imaging-based hippocampal volumetric analysis is a useful method to localize the origin of partial complex seizures.

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(click to filter results - removes previous filter) hippocampus mesial temporal sclerosis MRI MRI,abnormal MRI,volumetry seizure seizure,focal seizure,focus seizure,intractable seizure,psychomotor-temporal lobe

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